[…] (RPE) stably expressed human CXCR4 when transduced with N-terminal FLAG or N-terminal FLAG and C-terminal MYC tagged CXCR4. RPE cells were used because this cell line has very low CXCR4 […]
HR1 cells are HEK 293 cells stably expressing conditional kinase <U+2206>Raf-1:ER* from the pCMV Neo Myc plasmid. <U+2206>Raf-1:ER* (also known as <U+2206>CRAF:ER*) consists of the isolated kinase domain of c-Raf1 […]
CIP2A is an oncoprotein that inhibits PP2A tumor suppressor activity in human malignancies by preventing degredation of c-Myc and regulates the phosphorylation of many oncoproteins.
[…] vector expressing CaMPARI2_F391W (Kd = 110nM), a photoconvertible fluorescent protein-based calcium integrator, in neurons.Insert Size (bp): 1446Promoter: hsyn (synapsin-1)Tags / Fusion Proteins:NES_his (N terminal on insert)FLAG-HA- myc (C terminal on insert)
[…] vector expressing CaMPARI2_H396K (Kd = 360nM), a photoconvertible fluorescent protein-based calcium integrator, in neurons.Insert Size (bp): 1446Promoter: hsyn (synapsin-1)Tags / Fusion Proteins:NES_his (N terminal on insert)FLAG-HA- myc (C terminal on insert)
[…] vector expressing CaMPARI2_L398T (Kd = 825nM), a photoconvertible fluorescent protein-based calcium integrator, in neurons.Insert Size (bp): 1446Promoter: hsyn (synapsin-1)Tags / Fusion Proteins:NES_his (N terminal on insert)FLAG-HA- myc (C terminal on insert)
[…] for targets with key functions in tumour signalling pathways including tumour suppressors (p53, RB1), oncogenes (c- MYC), and tumour associated antigens (MUC1). Tumour suppressors Antibodies targeting p53, Retinoblastoma 1 (RB1), and […]
[…] instance of an innovative antibody contributed to CancerTool.org is the Anti-Omomyc- an antibody to study Myc biology, invented by Prof. Laura Soucek, co-Director at the Vall d’Hebron Institute of Oncology. It […]
[…] oncoprotein that inhibits PP2A tumor suppressor activity in human malignancies by preventing degredation of c- Myc and regulates the phosphorylation of many oncoproteins. CIP2A is required for malignant cellular growth […]
[…] in driving the growth of these cancers, most intriguingly by stabilizing the concentrations of the myc oncoprotein. This suggests that CD19 and its downstream signaling may be a more attractive […]
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.
