[…] role in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed primarily in haematopoietic cells and immature gastroepithelial cells.
[…] ability to bind cyclin E, and the SCF (FBW7) is now known to target c- Myc, c-Jun and Notch for degradation in addition to its role in cyclin E proteolysis. […]
[…] for targets with key functions in tumour signalling pathways including tumour suppressors (p53, RB1), oncogenes (c- MYC), and tumour associated antigens (MUC1). Tumour suppressors Antibodies targeting p53, Retinoblastoma 1 (RB1), and […]
[…] tumour immune escape. These signalling pathways include STAT3, β-Catenin, PI3K/PTEN/AKT/mTOR, p53, NF-κB, RAS/RAF/MAPK, and KRAS/ MYC. They can drive effective immunocyte exclusion and disfunction, as well as recruitment and differentiation […]
myc
[…] the TME Antibodies directed at epigenetic changes, and key molecules involved in signalling pathways like MYC and p53. By supplying these tools, we hope to equip scientists with the antibodies […]
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