UM-RC-2 (Human renal carcinoma) cell line

UM-RC-2 are a renal carcinoma cell line, established in long term culture, from surgically obtained renal carcinoma specimens of patients who underwent nephrectomy. This patient had metastatic disease at the time of nephrectomy.These cells were evaluated for their ability to form tumors in nude mice and were confirmed to produced clear cell tumors.

Contributors

Inventor Institute
H. Grossman University of Michigan
Cat. #: 160446
Tool sub type: 10XUAS IVS p10
Unit size: 1×10^6 cells / vial
Cancer types: Kidney cancer;Renal cancer
Research Fields: Cancer;Cancer
Organism: Human
Tissue: Kidney
Gender: Male
Model: Cancer Model
Growth properties: Adherent
Product description: UM-RC-2 are a renal carcinoma cell line, established in long term culture, from surgically obtained renal carcinoma specimens of patients who underwent nephrectomy. This patient had metastatic disease at the time of nephrectomy. Initial work suggests these cells grow well in primary culture but life expectancy is limited to less than 10 passages. These cells were evaluated for their ability to form tumors in nude mice and were confirmed to produced clear cell tumors. UM-RC-2 cells demonstrated low and high passage number autologous reactivity in Protein A assays.These cells are adherent and display a loss of contact inhibition. Doubling time is approximately 24 hours.
Gender: Male
CRISPR: Yes
Conditional: No
Disease: Cancer;Cancer
Format: Frozen
Shipping conditions: Dry ice
Growth medium: Cells were grown in Eagle's Minimum Essential Medium (EMEM) containing 1% nonessential amino acids, 2mM glutamine, 100U/ml penicillin, 100ug/ml streptomycin and 10% Fetal Bovine Serum (FBS).
Mycoplasma free: Yes
References:

Grossman et al. 1985. J Surg Oncol. 28(3):237-44. PMID: 4038766.

Images

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UM-RC-2 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)

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