#156418

Tamoxifen-resistant MCF7 Breast Cancer cell line

Cat. #156418

Tamoxifen-resistant MCF7 Breast Cancer cell line

Cat. #: 156418

Sub-type: Continuous

Unit size: 1x10^6 cells / vial

Disease: Cancer

Model: Cancer Model

£575.00

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Contributor

Inventor: Saraswati Sukumar

Institute: Johns Hopkins University

Tool Details
Target Details
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Tamoxifen-resistant MCF7 Breast Cancer cell line
  • Cancer: Breast cancer
  • Cancers detailed: Breast cancer
  • Research fields: Cancer;Drug development
  • Tool sub type: Continuous
  • Disease: Cancer
  • Model: Cancer Model
  • Description: MCF7 cells serve as a prototypic model system for human breast cancer and their response to secretive endocrine response modifiers (SERM) therapy. MCF7 cells, upon long term exposure to tamoxifen, acquire tam-resistance and continue to grow in the presence of tamoxifen. This provides a cell-based model , both in vitro and in vivo, for tam-resistant breast cancer, allows the testing of alternate therapies to tam-resistant breast cancer, or the high-throughput testing of drugs that might synergize with hormone based therapies.
  • Cellosaurus id: CVCL_EG55

Target Details

  • Target: tamoxifen resistant breast cancer

Handling

  • Format: Frozen
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice

References

  • Wu et al. 2015. Mol Cell Proteomics. 14(11):2887-900. PMID: 26330541.