Sdhb -/- CL 7 Cell Line

Please Enter Your Email ID
Email ID

Cat. #153293

Sdhb -/- CL 7 Cell Line

Cat. #: 153293

Unit size: 1x10^6 cells / vial

Availability: 3-4 weeks

Organism: Mouse

Tissue: Kidney

Disease: Cancer

Model: Knock-Out


This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.


Inventor: Eyal Gottlieb

Institute: Cancer Research UK, Glasgow: The Beatson Institute

Tool Details
Target Details
Related Tools

Tool Details


  • Name: Sdhb -/- CL 7 Cell Line
  • Alternate name: Succinate dehydrogenase, SDH, Succinate-coenzyme Q reductase, SQR
  • Research fields: Cancer;Drug development;Metabolism
  • Organism: Mouse
  • Tissue: Kidney
  • Disease: Cancer
  • Model: Knock-Out
  • Description: Succinate dehydrogenase (SDH) is an enzyme complex found in the inner mitochondrial membrane of mammalian mitochondria and many bacterial cells. SDH is the only enzyme that participates in both the electron transport chain and citric acid cycle. The enzymatic function of SDH oxidises succinate to fumarate in the tricarboxylic acid cycle and losing this function is associated with cancer formation.
  • Biosafety level: 1
  • Cellosaurus id: CVCL_HG13

Target Details

  • Target: Succinate dehydrogenase


  • Format: Frozen
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice
  • Storage conditions: Liquid Nitrogen
  • Mycoplasma free: Yes

Related Tools

  • Related tools: Sdhb -/- CL 5 Cell Line ; SDHB Floxed Mouse ; Sdhb fl/fl Cell Line


  • Cardaci et al. 2015. Nat Cell Biol. 17(10):1317-26. PMID: 26302408.
  • Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.