Cat. #162003
Melan-p53-2 cell line
Cat. #: 162003
Organism: Mouse
Tissue: Skin
Disease: Non-cancer
Model: Immortalised non-cancerous cell lines
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Elena Sviderskaya
Institute: St. George's University London
Primary Citation: Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. PMID: 11904317
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Melan-p53-2 cell line
- Organism: Mouse
- Tissue: Skin
- Disease: Non-cancer
- Morphology: Small, oval-fusiform
- Model: Immortalised non-cancerous cell lines
- Description: The melan-p53-1, -2 and -3 cell lines are immortal melanocyte cell lines derived from the skin of neonatal Tp53–/– C57BL/6J mice. The expression of Ink4a in these cells is supressed and Arf expression is diminished. These cells are visibly pigmented and display morphology typical of normal melanocytes and can be useful in studying the role of p53 in melanocytes.
- Application: Melanocyte cell biology
Applications
- Application: Melanocyte cell biology
Handling
- Growth medium: RPMI + FBS (10%) + TPA (200 nM) + cholera toxin (CT) (200 pM)
- Storage conditions: liquid N2
References
- Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20
- 94(6):446-54. PMID: 11904317
