Cat. #151282
Anti-XRCC2 [XRCC2 1G4/1]
Cat. #: 151282
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: XRay Repair Cross Complementing 2 (XRCC2)
Class: Monoclonal
Application: WB
Reactivity: Human ; Hamster
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Stephen West
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-XRCC2 [XRCC2 1G4/1]
- Research fields: Genetics;Microbiology
- Clone: XRCC2 1G4/1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 33 kDa
- Strain: Balb/c
- Reactivity: Human ; Hamster
- Host: Mouse
- Application: WB
- Description: X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
- Recommended controls: HeLa nuclear extracts
Target Details
- Target: XRay Repair Cross Complementing 2 (XRCC2)
- Molecular weight: 33 kDa
- Tissue cell line specificity: HeLa nuclear extracts
- Target background: X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Gildemeister et al. 2009. J Biol Chem. 284(46):31945-52. PMID: 19783859.
- Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C.
- Nagaraju et al. 2009. Mol Cell Biol. 29(15):4283-94. PMID: 19470754.
- XRCC2 and XRCC3 regulate the balance between short- and long-tract gene conversions between sister chromatids.
- French et al. 2002. J Biol Chem. 277(22):19322-30. PMID: 11912211.
- Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability.
