Von Willebrand factor (vWF) mediates platelet adhesion to injured endothelium, the first step in hemostasis, and helps maintain factor VIII levels. When vWF is deficient, patients have a bleeding disorder called von Willebrand disease (vWD).
| Inventor | Institute |
|---|---|
| Jacqueline Cordell | University of Oxford |
| Cat. #: | 151405 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Stem cell biology;Tissue-specific biology |
| Application: | ELISA ; IHC ; WB |
| Target: | Von Willebrand factor (VWF) |
| Reactivity: | Human |
| Clone: | F8/44/20 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Von Willebrand factor (vWF) mediates platelet adhesion to injured endothelium, the first step in hemostasis, and helps maintain factor VIII levels. When vWF is deficient, patients have a bleeding disorder called von Willebrand disease (vWD). |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Von Willebrand factor isolated from human plasma |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Von Willebrand factor (vWF) mediates platelet adhesion to injured endothelium, the first step in hemostasis, and helps maintain factor VIII levels. When vWF is deficient, patients have a bleeding disorder called von Willebrand disease (vWD). |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Falini et al. 1986. J Immunol Methods. 93(2):265-73. PMID: 2430024. Description of a sequential staining procedure for double immunoenzymatic staining of pairs of antigens using monoclonal antibodies. Falini et al. 1984. Br J Haematol. 56(3):365-86. PMID: 6365152. Immunohistological analysis of human bone marrow trephine biopsies using monoclonal antibodies. Naiem et al. 1982. J Immunol Methods. 50(2):145-60. PMID: 6806388. The value of immunohistological screening in the production… |
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