Anti-VEGF [VG-1]

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Cat. #151258

Anti-VEGF [VG-1]

Cat. #: 151258

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Vascular Endothelial Growth Factor (VEGF)

Class: Monoclonal

Application: ELISA ; IHC ; IF ; IP ; WB

Reactivity: Human

Host: Mouse


This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.


Inventor: Helen Turley

Institute: University of Oxford

Tool Details
Target Details

Tool Details


  • Name: Anti-VEGF [VG-1]
  • Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
  • Clone: VG-1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 19-22 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; IF ; IP ; WB
  • Description: Monoclonal antibody targeted at vascular endothelial growth factor (VEGF) is valuable for investigating VEGF and angiogenesis in pathological conditions particularly within cancer.
  • Immunogen: Recombinant VEGF Protein
  • Immunogen uniprot id: P15692
  • Isotype: IgG1
  • Myeloma used: P3/NS1/1-Ag4.1
  • Recommended controls: Corpus luteum, VEGF165 recombinant protein, astrocytoma or hemoangiosarcoma.

Target Details

  • Target: Vascular Endothelial Growth Factor (VEGF)
  • Molecular weight: 19-22 kDa
  • Tissue cell line specificity: Corpus luteum, VEGF165 recombinant protein, astrocytoma or hemoangiosarcoma.
  • Target background: VG-1 monoclonal antibody is directed against vascular endothelial growth factor (VEGF) isoforms 121, 165 and 189. VEGF is a 34-43 kD polypeptide growth factor, part of the PDGF family. There are 7 homo-dimeric isoforms (A-G) with VEGF 121, VEGF 165 and VEGF189 being the most extensively studied (F,D and B respectively). They are generated by alternative splicing and bind to VEGF receptors (FLT-1 and KDR) which are selectively expressed on vascular endothelial cells. VEGF elicits mitogenic effects on endothelial cells and is strongly angiogenic, with a role in cancer and metastasis. VEGF is involved in vasculogenesis and endothelial growth. The VEGF expression is potentiated and the protein is secreted by tumour cells in response to hypoxia, by activated oncogenes, growth factors, nitric oxide and a variety of cytokines. VEGF is an angiogenic growth factor and a prognostic indicator for cancer when detected in serum. VG-1 is useful for studies of VEGF and angiogenesis in human pathological material. Anti VG-1 was created to investigate the tissue distribution of VEGF in normal and pathological specimens with a stable and reliable reagent.


  • Application: ELISA ; IHC ; IF ; IP ; WB


  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4° C


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