Cat. #162381
Anti-TMEM59 C-terminus monoclonal antibody [7C6-4E5]
Cat. #: 162381
Sub-type: Primary antibody
Target: TMEM59, C-terminus
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Helmholtz Munich Core Facility Monoclonal Antibodies
Primary Citation: Ullrich et al. 2010. J Biol Chem. 2: 285(27):20664-74. PMID: 20427278
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-TMEM59 C-terminus monoclonal antibody [7C6-4E5]
- Alternate name: Anti TMEM59, C-terminus monoclonal antibody (clone 7C6-4E5)
- Cancers detailed: Bone
- Research fields: Cancer;Cell biology;Cell signaling and signal transduction
- Clone: 7C6-4E5
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Rat
- Disease: Cancer
- Application: WB
- Description: Antibody for TMEM59, also known as transmembrane protein 59. TMEM59 has been shown to modulate ectodomain shedding of the amyloid precursor protein (APP). Its expression is linked to cancer development and prognosis in some cancer types including bone cancer.
- Immunogen: GST fusion protein of amino acids 261–323 of TMEM59
- Isotype: IgG2b
Target Details
- Target: TMEM59, C-terminus
- Target alternate names: HSPC001, C1orf8, Liver Membrane-Bound Protein
- Target background: TMEM59, also known as transmembrane protein 59, has been shown to modulate ectodomain shedding of the amyloid precursor protein (APP). Its expression is linked to cancer development and prognosis in some cancer types including bone cancer.
Applications
- Application: WB
References
- Ullrich et al. 2010. J Biol Chem. 2: 285(27):20664-74. PMID: 20427278
