CD36 is a class B scavenger receptor found in vascular endothelium, platelets and monocytes. CD36 binds thrombospondin and oxidised low density lipoprotein (LDL).
| Inventor | Institute |
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| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| SKU: | 151160 |
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| Product description: | CD36 is a class B scavenger receptor found in vascular endothelium, platelets and monocytes. CD36 binds thrombospondin and oxidised low density lipoprotein (LDL). |
| Alternate name: | SMO |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Immunogen: | Tonsil cells and PBM |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Cat. #: | 151160 |
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| Provenance and Ownership: | The Anti-Thrombospondin receptor [SMT] is owned by Cancer Research UK. CancerTools supplies the Anti-Thrombospondin receptor [SMT] under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing Anti-Thrombospondin receptor [SMT] directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer; Cell biology; Cell signaling and signal transduction; Metabolism; Neurobiology; Stem cell biology; Tissue-specific biology |
| Application: | FACS ; IHC ; IP ; Fn ; WB |
| Target: | Thrombospondin receptor (CD36) |
| Reactivity: | Human |
| Clone: | SMT |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324. |
| Target background: | CD36 is a class B scavenger receptor found in vascular endothelium, platelets and monocytes. CD36 binds thrombospondin and oxidised low density lipoprotein (LDL). |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Pilling et al. 2009. PLoS One. 4(10):e7475. PMID: 19834619. Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts. Biswas et al. 2007. PLoS Pathog. 3(9):1271-80. PMID: 17907801. Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping. Pain et al. 2001. Proc Natl Acad Sci U S A. 98(4):1805-10. PMID: 11172032. Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria. Wintergerst et al. 2000. Eur J Biochem. 267(19):6050-9. PMID: 10998066. Apoptosis induced by oxidized low density lipoprotein in human monocyte-derived macrophages involves CD36 and activation of caspase-3. Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324. Monoclonal antibodies specific for human monocytes, granulocytes and endothelium. |
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