Anti-SPRED1 [M23-P2G3]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-SPRED1 [M23-P2G3]
• Research fields: Cancer;Cell signaling and signal transduction
• Clone: M23P2G3
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Strain: Balb/c
• Reactivity: Human
• Host: Mouse
• Application: ELISA ; IF ; WB
• Description: Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. SPRED1 can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in SPRED1 can cause neurofibromatosis type 1-like syndrome (NFLS) and contribute to Legius syndrome and childhood leukemia.
• Immunogen: Peptide Sequence YVPLRMCHR (amino acids 420 428)
• Isotype: IgG1 kappa
• Myeloma used: P3X63Ag8.653
• Recommended controls: ELISA- Peptide immunogenWestern Blot- Hela whole cell extractImmunofluorescence- Hela Cells

Target Details

• Target: Sprouty-Related, EVH1 Domain Containing 1 (SPRED1)
• Tissue cell line specificity: ELISA- Peptide immunogenWestern Blot- Hela whole cell extractImmunofluorescence- Hela Cells
• Target background: Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. SPRED1 can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in SPRED1 can cause neurofibromatosis type 1-like syndrome (NFLS) and contribute to Legius syndrome and childhood leukemia.

Applications

• Application: ELISA ; IF ; WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -20° C
• Shipping conditions: Dry ice