Cat. #151671
Anti-S100a9 [2B10]
Cat. #: 151671
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: S100a9
Class: Monoclonal
Application: IF ; FACS ; IHC ; IF ; IP ; WB
Reactivity: Mouse
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Nancy Hogg
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-S100a9 [2B10]
- Research fields: Cancer;Cell signaling and signal transduction;Immunology
- Clone: 2B10
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Mouse
- Host: Rat
- Application: IF ; FACS ; IHC ; IF ; IP ; WB
- Description: The mAb is specific for mouse S100a9 protein that forms a heterodimer with S100a8 and constitutes 45% of the neutrophil cytosolic protein. The mAb stains neutrophils strongly and monocytes weakly.
- Immunogen: Recombinant full-length murine S100a9
- Isotype: IgG1 kappa
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Neutrophils
Target Details
- Target: S100a9
- Tissue cell line specificity: Neutrophils
- Target background: The mAb is specific for mouse S100a9 protein that forms a heterodimer with S100a8 and constitutes 45% of the neutrophil cytosolic protein. The mAb stains neutrophils strongly and monocytes weakly.
Applications
- Application: IF ; FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Colom et al. 2015. Immunity. 42(6):1075-86. PMID: 26047922.
- Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo.
- Chen et al. 2015. Mucosal Immunol. 8(2):390-402. PMID: 25160819.
- IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology.
- Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
- Voisin et al. 2010. Am J Pathol. 176(1):482-95. PMID: 20008148.
- Venular basement membranes ubiquitously express matrix protein low-expression regions: characterization in multiple tissues and remodeling during inflammation.
- Young et al. 2007. Br J Pharmacol. 151(5):628-37. PMID: 17471175.
- Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice.
- Hobbs et al. 2003. Mol Cell Biol. 23(7):2564-76. PMID: 12640137.
- Myeloid cell function in MRP-14 (S100A9) null mice.
