#153988

Anti-phospho Sam68, Ser113/117

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Cat. #153988

Anti-phospho Sam68, Ser113/117

Cat. #: 153988

Sub-type: Primary antibody

Unit size: 100 ug

Target: Sam68(Src-associatedduringmitosis,68 kDa)

Class: Polyclonal

Application: IHC ; WB

Reactivity: Human ; Mouse ; Rat

Host: Rabbit

£300.00

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Contributor

Inventor: Fengyi Wan

Institute: Johns Hopkins University

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-phospho Sam68, Ser113/117
  • Alternate name: KH domain-containing, RNA-binding, signal transduction-associated protein 1, GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, p21 Ras GTPase-activating protein-associated p62, p68
  • Cancer: Gynaecologic cancer
  • Cancers detailed: Ovarian
  • Research fields: Apoptosis and autophagy;Cell biology;Cell signaling and signal transduction;Genetics
  • Tool sub type: Primary antibody
  • Class: Polyclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Molecular weight: 68 kDa
  • Reactivity: Human ; Mouse ; Rat
  • Host: Rabbit
  • Application: IHC ; WB
  • Description: Sam68 (KHDRBS1 also known as KH domain-containing, RNA-binding, signal transduction-associated protein 1) is a RNA binding protein that binds to U(U/A)AA direct repeats to regulate RNA splicing, transcription, RNA metabolism, signal transduction, the cell cycle and apoptosis. Post-translational modifications on Sam68 is what allows it to regulate many different cellular process. For instance, when Sam68 is phosphorylated, on serine 113 and 117, it forms nuclear factor-kappaB (NF-Î?B) compl...
  • Immunogen: Synthetic peptide (NH2-CAEKD(Sp)LDP(Sp)FTH-COOH)

Target Details

  • Target: Sam68(Src-associatedduringmitosis,68 kDa)
  • Molecular weight: 68 kDa
  • Tissue cell line specificity: Rabbit
  • Target background: Sam68 (KHDRBS1 also known as KH domain-containing, RNA-binding, signal transduction-associated protein 1) is a RNA binding protein that binds to U(U/A)AA direct repeats to regulate RNA splicing, transcription, RNA metabolism, signal transduction, the cell cycle and apoptosis. Post-translational modifications on Sam68 is what allows it to regulate many different cellular process. For instance, when Sam68 is phosphorylated, on serine 113 and 117, it forms nuclear factor-kappaB (NF-B) co...

Applications

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Fu et al. 2013. Nat Commun. 4:1909. PMID: 23715268.
  • Sam68 modulates the promoter specificity of NF-B and mediates expression of CD25 in activated T cells.