Cat. #162060
Anti-phospho-s392 p53 [FPS392]
Cat. #: 162060
Sub-type: Primary antibody
Target: tumour suppressor p53 protein phosphorylated at serine 392
Class: Monoclonal
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Moravian Biotechnology
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-phospho-s392 p53 [FPS392]
- Clone: FPS392
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 53 kDa
- Reactivity: Human
- Host: Mouse
- Description: Antibody created to detect the p53 protein phosphorylated at serine 392. Binding specificity: recognizes human phosphorylated form of p53 at serine 392, epitope set with phage-display is EGPDS[Phos]D.
- Isotype: IgG1 kappa
- Production details: B cell donor: Splenocytes from mouse immunised with the C-terminal phospho-peptide sequence RKKLMFKTEGPDS[Phos]D of p53, Fusion partner: SP2
Target Details
- Target: tumour suppressor p53 protein phosphorylated at serine 392
- Molecular weight: 53 kDa
- Target background: p53 plays a key role in tumor suppression. The tumor suppressive function of p53 has long been attributed to its ability to induce apoptosis, cell cycle arrest, and senescence in cells. However, recent studies suggest that other functions of p53 also contribute to its role as a tumor suppressor, such as its function in metabolic regulation.
- Epitope sequence: RKKLMFKTEGPDS[pho]D
Handling
- Format: Liquid
