Cat. #151619
Anti-MMP2 [4D3]
Cat. #: 151619
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Human matrix metalloproteinase 2 (MMP-2)
Class: Monoclonal
Application: ELISA ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-MMP2 [4D3]
- Research fields: Cancer;Cell biology;Genetics;Metabolism;Tissue-specific biology
- Clone: 4D3
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; IF ; IP ; WB
- Description: MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome.
- Immunogen: Ovalbumin-conjugated synthetic peptide; TSLGLPPDVQRVD
- Isotype: IgG1
- Myeloma used: P3X63Ag8.653
- Recommended controls: IHC: formalin-fixed, paraffin-embedded lung containing intra-alveolar macrophageswestern blot: rhMMP-2, 400 ng per lane
Target Details
- Target: Human matrix metalloproteinase 2 (MMP-2)
- Tissue cell line specificity: IHC: formalin-fixed, paraffin-embedded lung containing intra-alveolar macrophageswestern blot: rhMMP-2, 400 ng per lane
- Target background: MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome.
Applications
- Application: ELISA ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -80° C
- Shipping conditions: Shipping at 4° C
References
- Jeffery et al. 2009. Histopathology. 54(7):820-8. PMID: 19635101.
- The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers.
- Lyall et al. 2006. Clin Cancer Res. 12(4):1184-91. PMID: 16489072.
- Profiling markers of prognosis in colorectal cancer.
- Curran et al. 2004. Clin Cancer Res. 10(24):8229-34. PMID: 15623598.
- Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
- Murray et al. 1998. Gut. 43(6):791-7. PMID: 9824606.
- Matrix metalloproteinases and their inhibitors in gastric cancer.
- Murray et al. 1998. J Pathol. 185(3):256-61. PMID: 9771478.
- Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer.
