It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
| Institute |
|---|
| University of Birmingham |
| Cat. #: | 151486 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Immunology |
| Application: | FACS |
| Target: | Lewis X (CD15) |
| Reactivity: | Human |
| Clone: | BU28 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX |
|---|---|
| Product description: | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of HodgkinÄËĂÂĂÂs disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin's disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Knapp et al. 1989. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, Oxford. Zhang et al. 1998. Hybridoma. 17(5):445-56. PMID: 9873990. Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells. |
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