#151177

Anti-Leu2 [UCH-T4]

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Cat. #151177

Anti-Leu2 [UCH-T4]

Cat. #: 151177

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Leu2 (CD8)

Class: Monoclonal

Application: FACS ; IHC ; IF

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Peter Beverley

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Leu2 [UCH-T4]
  • Research fields: Immunology;Stem cell biology
  • Clone: UCH-T4
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 32 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF
  • Description: UCH-T4 is recommended for: the detection of immunoregulatory T cell subset imbalances in autoimmune disorders and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma in conjunction with other antigens and determination of T4/T8 ratios in immune deficiencies, rheumatoid arthritis, multiple sclerosis, etc.
  • Immunogen: Thymocytes followed by Sezary T cells.
  • Isotype: IgG2a

Target Details

  • Target: Leu2 (CD8)
  • Molecular weight: 32 kDa
  • Target background: Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells.

Applications

  • Application: FACS ; IHC ; IF

Handling

  • Format: Liquid
  • Concentration: 0.9 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Beverley P. 1982. Proc. Royal Soc. Edin. 81B:221-232
  • Waleh et al. 2011. Pediatr Res. 70(4):332-8. PMID: 21691249.
  • Anatomic closure of the premature patent ductus arteriosus: The role of CD14+/CD163+ mononuclear cells and VEGF in neointimal mound formation.
  • Martn et al. 2002. J Cutan Pathol. 29(6):347-53. PMID: 12135465.
  • Vascular endothelium express CS-1 fibronectin in allergic contact dermatitis.
  • Kee et al. 2000. J Cell Biochem. 78(1):97-111. PMID: 10797569.
  • beta1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum.