Cat. #151179
Anti-L1CAM [UJ181.4]
Cat. #: 151179
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: L1 cell adhesion molecule (L1CAM; CD171)
Class: Monoclonal
Application: IHC ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: John Kemshead
Institute: Institute of Child Health
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-L1CAM [UJ181.4]
- Research fields: Cell biology;Cell signaling and signal transduction;Neurobiology
- Clone: UJ181.4
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 220-240 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IP ; WB
- Description: Used in diagnosis of primitive neuroectodermal tumours. Binds to tumours of neural and glial origin and does not bind to paediatric or adult brain. Used for bone marrow purging and intrathecal targeting
- Immunogen: 16 week human foetal brain.
- Isotype: IgG1
- Myeloma used: P3X63Ag8.653
Target Details
- Target: L1 cell adhesion molecule (L1CAM; CD171)
- Molecular weight: 220-240 kDa
- Target background: Used in diagnosis of primitive neuroectodermal tumours. Binds to tumours of neural and glial origin and does not bind to paediatric or adult brain. Used for bone marrow purging and intrathecal targeting
Applications
- Application: IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Garson.JA. 1983. MD Thesis. Birmingham
- Bourne et al. 1989. Hybridoma. 8(4):415-26. PMID: 2550359.
- Monoclonal antibodies M340 and UJ181.4 recognize antigens associated with primitive neuroectodermal tumours/tissues.
- Coakham et al. 1985. J Clin Pathol. 38(2):165-73. PMID: 3881481.
- Immunohistological diagnosis of central nervous system tumours using a monoclonal antibody panel.
- Kemshead et al. 1983. Int J Cancer. 31(2):187-95. PMID: 6826247.
- Monoclonal antibody UJ 127:11 detects a 220,000-240,000 kdal. glycoprotein present on a sub-set of neuroectodermally derived cells.
