Cat. #151104
Anti-Integrin a2 [HAS-3]
Cat. #: 151104
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Integrin a2 (CD49b)
Class: Monoclonal
Application: FACS ; IHC ; IF ; IP
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Fiona Watt
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Integrin a2 [HAS-3]
- Alternate name: Integrin Subunit Alpha 2; Alpha 2 Subunit Of VLA-2 Receptor; Platelet Membrane Glycoprotein Ia; CD49 Antigen-Like Family Member B; Collagen Receptor; CD49B; GPIa; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; Human Platelet Alloantigen System 5; Platelet Glycoprotein GPIa; Platelet Antigen Br; VLA-2 Subunit Alpha; CD49b Antigen; HPA-5; VLA-2; VLAA2; BR
- Research fields: Cell biology;Cancer;Cell signaling and signal transduction;Metabolism
- Clone: HAS-3
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF ; IP
- Description: Monoclonal antibody which co-precipitates a2b1 integrin from keratinocytes and inhibits a2b1 motility in collagen.
- Immunogen: Whole human keratinocytes.
- Immunogen uniprot id: P17301
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Integrin a2 (CD49b)
- Target background: Monoclonal antibody which co-precipitates a2b1 integrin from keratinocytes and inhibits a2b1 motility in collagen.
Applications
- Application: FACS ; IHC ; IF ; IP
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Shipping at 4° C
References
- Activation of c-MET induces a stem-like phenotype in human prostate cancer.
- van Leenders et al. 2011. PLoS One. 6(11):e26753. PMID: 22110593.
- Teklemariam et al. 2011. Toxicon. 57(5):646-56. PMID: 21255601.
- Fn analysis of a recombinant PIII-SVMP, GST-acocostatin
- an apoptotic inducer of HUVEC and HeLa, but not SK-Mel-28 cells.
- Singh et al. 2010. Am J Physiol Lung Cell Mol Physiol. 299(2):L169-83. PMID: 20435685.
- Can lineage-specific markers be identified to characterize mesenchyme-derived cell populations in the human airways?
- Alford et al. 1998. J Cell Sci. 111 ( Pt 4):521-32. PMID: 9443900.
- Integrin-matrix interactions affect the form of the structures developing from human mammary epithelial cells in collagen or fibrin gels.
- Tenchini et al. 1993. Cell Adhes Commun. 1(1):55-66. PMID: 7521749.
- Evidence against a major role for integrins in calcium-dependent intercellular adhesion of epidermal keratinocytes.
