#151167

Anti-HPV16E2 [TVG 261]

Cat. #151167

Anti-HPV16E2 [TVG 261]

Cat. #: 151167

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Human Papilloma virus-16 early protein 2 (HPV16 E2)

Class: Monoclonal

Application: IP ; WB ; ELISA ; IF ; WB

Reactivity: Human papilloma virus

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: University of Cambridge

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-HPV16E2 [TVG 261]
  • Cancer: Gynaecologic cancer
  • Cancers detailed: Cervical
  • Research fields: Cancer;Microbiology
  • Clone: TVG 261
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 10 kDa
  • Strain: Balb/c
  • Reactivity: Human papilloma virus
  • Host: Mouse
  • Application: IP ; WB ; ELISA ; IF ; WB
  • Description: TVG 261 is useful for detection of protein in cervical lesions.
  • Immunogen: Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE).
  • Isotype: IgG1
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Human Papilloma virus-16 early protein 2 (HPV16 E2)
  • Molecular weight: 10 kDa
  • Target background: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication.

Applications

  • Application: IP ; WB ; ELISA ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Evans et al. 2019. J Virol. 93(4):. PMID: 30518656.
  • Ludwig et al. 2018. Front Oncol. 8:445. PMID: 30370252.
  • Evans et al. 2017. Oncotarget. 8(47):81892-81909. PMID: 29137231.
  • Campos-Len et al. 2017. J Virol. 91(5):. PMID: 28031358.
  • A deletion in the gene encoding the CD45 antigen in a patient with SCID.
  • A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans.
  • Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.
  • The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.