Cat. #160587
Anti-hEMILIN2 [hEMIL2]
Cat. #: 160587
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: hEMILIN2
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Alfonso Colombatti ; Maurizio Mongiat ; Roberto Doliana ; Maria Teresa Mucignat
Institute: National Cancer Institute CRO - Aviano
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-hEMILIN2 [hEMIL2]
- Research fields: Apoptosis and autophagy;Cancer;Cell biology;Cell signaling and signal transduction
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Emilin-2 (Elastin Microfibril Interface Located proteIN) is an extracellular matrix glycoprotein. Is part of a protein family which have been shown to be expressed in smooth muscle and other mesenchymal tissues and is localized at the proximity of elastin and microfibrils. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is involved in regulation of the extrinsic apoptotic pathway, by interacting with death receptors DR4 and DR5 and down-modulates the Wnt signalling pathway. EMILIN2 is also involved in the regulation of angiogenesis and elastogenesis
- Immunogen: Recombinant human Emilin-2 as immunizing antigen; BALB/c mice as host
- Recommended controls: IgG2b kappa
Target Details
- Target: hEMILIN2
- Tissue cell line specificity: IgG2b kappa
- Target background: Emilin-2 (Elastin Microfibril Interface Located proteIN) is an extracellular matrix glycoprotein. Is part of a protein family which have been shown to be expressed in smooth muscle and other mesenchymal tissues and is localized at the proximity of elastin and microfibrils. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is involved in regulation of the extrinsic apoptotic pathway, by interacting with death receptors DR4 and DR5 and down-modulates the Wnt signall...
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Storage conditions: Store at 2 - 8° C or aliquots at -20° C. Avoid repeated freeze-thaw cycles
- Shipping conditions: Dry ice
Related Tools
- Related tools: Anti-mEMILIN1 [mEMIL] monoclonal antibody ; Anti-hEMILIN1 [hEMIL1] monoclonal antibody ; Anti-mMMRN2 [mMMRN2] monoclonal antibody
References
- Marastoni et al. 2014. J Pathol. 232(4):391-404. PMID: 24374807.
- Mongiat et al. 2010. Neoplasia. 12(4):294-304. PMID: 20360940.
- Mongiat et al. 2007. Mol Cell Biol. 27(20):7176-87. PMID: 17698584.
