Anti-Estrogen Receptor Beta2 [57/3]

Clone 57/3 recognizes Estrogen Receptor Beta (ER?) 2 and is useful in determining the expression of ER?2 in cancer cells via various analysis methods.

Contributors

Institute
BioServ UK Ltd
Cat. #: 153632
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Ovarian cancer, Breast cancer
Research Fields: Cancer;Immunology
Application: IHC ; IF ; WB
Target: Estrogen Receptor ? 2
Reactivity: Human
Clone: 57/3
Host: Mouse
Class: Monoclonal
Alternate name: Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2
Product description: Estrogen receptors are commonly over-expressed in cancers. Clone 57/3 recognizes Estrogen Receptor Beta (ERÎ?) 2 and is useful in determining the expression of ERÎ?2 in cancer cells via various analysis methods.
Conjugation: Unconjugated
Isotype: IgG1
Molecular weight: 53 kDa
Immunogen: Recognizes ER?2 isomer at sequence CGMKMETLLPEATMEQ
Myeloma used: Sp2/0-Ag14
Target background: Estrogen receptors are commonly over-expressed in cancers. Clone 57/3 recognizes Estrogen Receptor Beta (ER?) 2 and is useful in determining the expression of ER?2 in cancer cells via various analysis methods.
Format: Liquid
Shipping conditions: Dry ice
References:

Buttarelli et al. 2017. Gynecol Oncol. 145(2):352-360. PMID: 28228232.

Hormone receptor expression profile of low-grade serous ovarian cancers.

Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.

Sexual dimorphism in medulloblastoma features.

Gender effect in experimental models of human medulloblastoma: does the estrogen receptor ? signaling play a role?

Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.

Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.

Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.

Carpino et al. 2007. Eur J Endocrinol. 157(2):239-44. PMID: 17656605.

Detection of aromatase and estrogen receptors (ERalpha, ERbeta1, ERbeta2) in human Leydig cell tumor.

Skliris et al. 2006. Br J Cancer. 95(5):616-26. PMID: 16880783.

Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours.

Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.

ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.

Sierens et al. 2004. J Mol Endocrinol. 32(3):703-18. PMID: 15171710.

Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and Fn analysis.

Critchley et al. 2002. J Clin Endocrinol Metab. 87(11):5265-73. PMID: 12414901.

Wild-type estrogen receptor (ERbeta1) and the splice variant (ERbetacx/beta2) are both expressed within the human endometrium throughout the normal menstrual cycle.

Ogawa et al. 1998. Nucleic Acids Res. 26(15):3505-12. PMID: 9671811.

Molecular cloning and characterization of human estrogen receptor betacx: a potential inhibitor ofestrogen action in human.

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