#154737

Anti-CD49E (Integrin Alpha 5) [SAM1]

Cat. #154737

Anti-CD49E (Integrin Alpha 5) [SAM1]

Cat. #: 154737

Sub-type: Primary antibody

Unit size: 100 ug

Target: CD49E

Class: Monoclonal

Application: FACS ; IHC ; IP

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Arnoud Sonnenberg

Institute: Netherlands Cancer Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-CD49E (Integrin Alpha 5) [SAM1]
  • Alternate name: ITGA5
  • Research fields: Cell biology;Cell signaling and signal transduction
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 135 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IP
  • Description: The ITGA5 gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling
  • Immunogen: U 937 cells
  • Isotype: IgG2b
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: CD49E
  • Molecular weight: 135 kDa
  • Target background: The ITGA5 gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling

Applications

  • Application: FACS ; IHC ; IP

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Sopp et al. 1997. Vet Immunol Immunopathol. 56(1-2):11-25. PMID: 9220577.
  • te Velde et al. 1988. J Immunol. 140(5):1548-54. PMID: 3279117.