Cat. #154761
Anti-CD227 (MUC1) [175C5]
Cat. #: 154761
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD227
Class: Monoclonal
Application: EM (EM) ; ELISA ; FACS ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Netherlands Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD227 (MUC1) [175C5]
- Alternate name: Mucin 1, Cell Surface Associated
- Cancer: Breast cancer;Gynaecologic cancer
- Cancers detailed: Breast cancer;Broadly Applicable;Colon;Ovarian
- Research fields: Cancer;Cell signaling and signal transduction
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 120 kDa
- Reactivity: Human
- Host: Mouse
- Application: EM (EM) ; ELISA ; FACS ; IHC ; IF ; IP ; WB
- Description: MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers
- Immunogen: Milkfat globule membranes
- Isotype: IgG1
Target Details
- Target: CD227
- Molecular weight: 120 kDa
- Target background: MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers
Applications
- Application: EM (EM) ; ELISA ; FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Hilkens et al. 1995. Biochem Soc Trans. 23(4):822-6. PMID: 8654846.
