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#151174

Anti-CD14 [UCH-M1] mAb

Cat. #151174

Anti-CD14 [UCH-M1] mAb

Cat. #: 151174

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: CD14

Class: Monoclonal

Application: FACS ; IHC ; IF

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Peter Beverley

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-CD14 [UCH-M1] mAb
  • Alternate name: CD14 Molecule; CD14 Antigen; Myeloid Cell-Specific Leucine-Rich Glycoprotein
  • Research fields: Cell biology;Immunology;Stem cell biology;Tissue-specific biology
  • Clone: UCH-M1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 52 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF
  • Description: UCH-M1 can be used to investigate specific in vitro antibody responses to influenza virus by human lymphocytes.
  • Immunogen: Thymocytes and peripheral blood leucocytes (PBL)
  • Immunogen uniprot id: P08575
  • Isotype: IgG2a
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: CD14
  • Molecular weight: 52 kDa
  • Target background: CD14 is found in human monocytes and vascular endothelium in some tissues. CD14 binds the endotoxin lipopolysaccharide.

Applications

  • Application: FACS ; IHC ; IF

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

Related Tools

  • Related tools: Anti-CD45RO, Recombinant [UCH-L1]

References

  • Sadeghi et al. 2016. PLoS One. 11(10):e0162667. PMID: 27695085.
  • GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.
  • Goya et al. 2006. Prostate. 66(15):1573-84. PMID: 16927388.
  • Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer.
  • Puig-Krger et al. 2004. J Biol Chem. 279(24):25680-8. PMID: 15070901.
  • Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages.
  • Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
  • Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.
  • Mitchell et al. 1983. Immunology. 50(2):239-50. PMID: 6578194.
  • Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes.

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