#162045

Melb-s3 cell line

Cat. #162045

Melb-s3 cell line

Cat. #: 162045

Organism: Mouse

Tissue: Skin

Model: Immortalised non-cancerous cell lines

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Elena Sviderskaya

Institute: St. George's University London

Tool Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Melb-s3 cell line
  • Organism: Mouse
  • Tissue: Skin
  • Morphology: Small, oval-fusiform
  • Model: Immortalised non-cancerous cell lines
  • Description: The melb-s1, -s2 and s3 lines are immortal melanoblast cell lines derived from the skin of neonatal Ednrbs/Ednrbs C3H mice. These cells express dopachrome tautomerase (also referred to as tyrosinase-related protein 2) but generally do not express tyrosinase. These cells are unpigmented. Melanocytes, irreversibly differentiated from melb-s1 melanoblasts (melan-s1) are also available from CancerTools.org. This melanoblast line is useful for developmental studies and, as melanoblasts display mechanisms similar to tumour cells (migration to and invasion of the epidermis) they may be a useful tool in studies of melanoma development.
  • Application: Melanocyte cell biology

Applications

  • Application: Melanocyte cell biology

Handling

  • Growth medium: RPMI + FBS (10%) + fibroblast growth factor 2 (FGF2) (40 pM) + mouse stem cell factor (mSCF) (20 ng/ml)
  • Storage conditions: liquid N2