IAHF Intralobular Human Fibroblast Cell Line

CD105high/CD26low lobular fibroblasts have been shown to grow in culture maintaining its CD105/CD26 phenotype and functional distinction.

Contributors

Inventor Institute
Mikkel Morsing ; Lone Ronnov-Jessen University of Copenhagen
Cat. #: 153783
Unit size: 1×10^6 cells / vial
Research Fields: Cell biology;Stem cell biology
Alternate name: IAHF Intralobular Human Fibroblast Cell Line, CD105 high/CD26 low lobular fibroblasts
Product description: CD105high/CD26low lobular fibroblasts have been shown to grow in culture maintaining its CD105/CD26 phenotype and functional distinction. Furthermore, the CD105high/CD26low lobular fibroblasts are distinguished by their capacity to differentiate into adipogenic and osteogenic lineages. Moreover, upon exposure to serum originally shown to reveal myofibroblastic differentiation in normal breast fibroblasts, the gene expression profile of CD105high/CD26low partly overlaps with the profile of breast tumour stoma.
Format: Frozen
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry ice
Mycoplasma free: Yes
Biosafety level: 1
References:

Morsing et al. 2016. Breast Cancer Res. 18(1):108. PMID: 27809866.

Morsing et al. 2020. Breast Cancer Res. 22(1):102. PMID: 32993755.

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