#153763

Family 1 sibling – LAD-III Lymphoblastoid Cell Line

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Cat. #153763

Family 1 sibling – LAD-III Lymphoblastoid Cell Line

Cat. #: 153763

Unit size: 1x10^6 cells / vial

Availability: 3-5 days

Organism: Human

Tissue: Blood

Disease: Cancer

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Nancy Hogg

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Family 1 sibling – LAD-III Lymphoblastoid Cell Line
  • Alternate name: Fermitin family homolog 3, MIG2-like protein, Unc-112-related protein 2
  • Cancer: Blood cancer
  • Cancers detailed: Leukocyte Adhesion Deficiency-III (LAD-III)
  • Research fields: Cell biology;Immunology
  • Organism: Human
  • Tissue: Blood
  • Disease: Cancer
  • Growth properties: Suspension, lymphoblastoid cell line
  • Description: An EBV-transformed B lymphoblastoid cell line (LCL) derived from the sister of a Maltese subject that has Leukocyte Adhesion Deficiency-III (LAD-III) with a mutation in the kindlin-3 gene. LCLs are also available from the subject, father and mother. This cell line was derived from 'Family 1 sibling' as described in Svensson et al. 2009. N.Nat Med. 2009 Mar;15(3):306-12. PMID: 1923446
  • Biosafety level: 1

Target Details

  • Target: Kindlin-3, UniProt ID:Q86UX7

Handling

  • Format: Frozen
  • Growth medium: RPMI-1640 + 10% FCS
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice
  • Storage conditions: Liquid Nitrogen
  • Mycoplasma free: Yes

Related Tools

  • Related tools: Family 1 subject - LAD-III Lymphoblastoid Cell Line ; Family 1 mother - LAD-III Lymphoblastoid Cell Line ; Family 1 father - LAD-III Lymphoblastoid Cell Line

References

  • Svensson et al. 2009. Nat Med. 15(3):306-12. PMID: 19234463.
  • Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.