#157990

CD47 Knock-out cell line

Cat. #157990

CD47 Knock-out cell line

Cat. #: 157990

Sub-type: Continuous

Unit size: 1x10^6 cells / vial

Organism: Mouse

Tissue: Skin

Disease: Cancer

Model: Knock-Out

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Binghamton University

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: CD47 Knock-out cell line
  • Cancer: Skin cancer
  • Cancers detailed: Melanoma;Tumor microenvironment
  • Research fields: Cancer;Cell signaling and signal transduction;Drug development
  • Tool sub type: Continuous
  • Parental cell: B16F10
  • Organism: Mouse
  • Tissue: Skin
  • Disease: Cancer
  • Model: Knock-Out
  • Description: CRISPR/Cas9 edited B16F10 cell line designed to help uncover the impact of editing a cell surface protein (CD47), in a tumor microenvironment, and its use as a whole-cell vaccine. CRISPR edited B16F10 cells.
  • Production details: Cells were cultured in high glucose DMEM and supplemented with 10% v/v Fetal Bovine Serum (FBS)
  • Additional notes: CRISPR edited B16F10 cells. Cancer Research Technology Limited (trading research tools as Ximbio) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here. This license from ERS Genomics Ltd allows Ximbio to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. Ximbio can pro...
  • Recommended controls: B16F10 parental cells

Target Details

  • Target: CD47

Applications

  • Application notes: Cancer Research Technology Limited (trading research tools as CancerTools.org) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here: https://www.cancertools.org/tool-faqs#hs_cos_wrapper_widget_1649861453796 This license from ERS Genomics Ltd allows CancerTools.org to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. CancerTools.org can provide these modified CRISPR-Cas9 cell lines to comp...

Handling

  • Format: Frozen
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice

References

  • Inducing Tumor Suppressive Microenvironments through Genome Edited CD47 -/- Syngeneic Cell Vaccination