CD47 Knock-out cell line

CRISPR/Cas9 edited B16F10 cell line designed to help uncover the impact of editing a cell surface protein (CD47), in a tumor microenvironment, and its use as a whole-cell vaccine.

Contributors

Institute
Binghamton University
Cat. #: 157990
Tool sub type: Continuous
Unit size: 1×10^6 cells / vial
Cancer types: Skin cancer
Research Fields: Cancer;Cell signaling and signal transduction;Drug development
Organism: Mouse
Tissue: Skin
Model: Knock-Out
Cancer Types In Detail: Melanoma;Tumor microenvironment
Product description: CRISPR/Cas9 edited B16F10 cell line designed to help uncover the impact of editing a cell surface protein (CD47), in a tumor microenvironment, and its use as a whole-cell vaccine. CRISPR edited B16F10 cells.
Production details: Cells were cultured in high glucose DMEM and supplemented with 10% v/v Fetal Bovine Serum (FBS)
Additional notes: CRISPR edited B16F10 cells. Cancer Research Technology Limited (trading research tools as Ximbio) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here. This license from ERS Genomics Ltd allows Ximbio to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. Ximbio can pro…
Parental cell line: B16F10
disease: Cancer
Format: Frozen
Shipping conditions: Dry ice
Recommended controls: B16F10 parental cells
References:

Inducing Tumor Suppressive Microenvironments through Genome Edited CD47 -/- Syngeneic Cell Vaccination

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