BCH-RB43 Retinoblastoma cell line

Retinoblastoma is a rare type of eye cancer most commonly affecting children under the age of 5. One eye can be affected, which is called unilateral retinoblastoma. Bilateral retinoblastoma is when both eyes are affected. This can be very distressing and frightening for the child and their parents._x000D_ _x000D_ Some children are born with a […]

Contributors

Inventor Institute
Carmel McConville University of Birmingham
Cat. #: 160610
Tool sub type: Primary
Unit size: 1×10^6 cells / vial
Cancer types: Eye cancer
Research Fields: Cancer
Organism: Human
Gender: Male
Model: BCOR mutation present
Cancer Types In Detail: Retinoblastoma
Product description: Retinoblastoma is a rare type of eye cancer most commonly affecting children under the age of 5. One eye can be affected, which is called unilateral retinoblastoma. Bilateral retinoblastoma is when both eyes are affected. This can be very distressing and frightening for the child and their parents.Some children are born with a change mutation in the RB1 retinoblastoma gene inherited from one of their parents. Or this gene change happened during the very early stages of their development in the womb. About 4 out of 10 children diagnosed (about 40%) have this heritable type, which often affects both eyes. Retinoblastoma tends to develop in just one eye in children who do not have this heritable type.We don't know what causes the remaining 60% of retinoblastomas. But these non inherited types nearly always only affect one eye.https://www.cancerresearchuk.org/about-cancer/childrens-cancer/eye-cancer-retinoblastoma/about
Gender: Male
Additional notes: STR data available on request
Cellosaurus ID: TBC
disease: Cancer
Format: Frozen
Shipping conditions: Dry ice
Growth medium: Culture conditions: DME/F12 + 15% fetal calf serum + glutamine + non-essential amino acids + beta-mercaptoethanol – dilute fresh stock of b-ME and add just before use (Carmel needs to check concentrations). Cell line is very slow growing and should only be split at high density (e.g. 2x 25cm flasks -> 3 flasks). Before splitting, shake flask gently to dislodge apoptotic cells from surface of clumps, allow clumps to settle, remove medium/cell debris and replace with fresh medium. Do not comp…

Related Tools for Cell lines

Cat. # Tool Name
151445 1-7HB2 Cell Line Key Info View Tool
151629 MEF Raf1 FF/FF KI Cell Line Key Info View Tool
151630 PDVC57B Cell Line Key Info View Tool
151665 MEF PKCe KO Cell Line Key Info View Tool
151448 CMT 167 Cell Line Key Info View Tool

Related News

UM-UC-10 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.
Cell Lines

Popular cell lines now available only from CancerTools.org

Read More
Cell Lines

New cell lines: murine melanocyte and melanoblast cell lines from Dr. Elena Sviderskaya

Read More
Image Reference: 2x PTEN -/- mouse prostate cancer cell lines (MuCap system). Histology staining of syngraft tumours (Van Duijn et al., 2018).
Cell Lines

38 new prostate cancer cell lines

Read More

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.