Anti-WSTF [WSTF]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-WSTF [WSTF]
• Cancer type: Breast cancer
• Cancers detailed: Breast cancer
• Research fields: Genetics
• Clone: WSTF
• Tool sub type: Primary antibody
• Class: Polyclonal
• Purpose: Marker
• Conjugation: Unconjugated
• Molecular weight: 170 kDa
• Reactivity: Human ; Mouse
• Host: Rabbit
• Application: IF ; IP ; WB
• Description: The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its functional motifs include a PHD zinc finger motif followed by a bromodomain. Both motifs are found in many transcription factors, suggesting that WSTF may function as a transcription factor. WSTF forms a chromatinremodelling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The droso...
• Immunogen: Peptide coupled to keyhole limpet hemocyanin.
• Recommended controls: ES, NIH 3T3, and HeLa cells

Target Details

• Target: Williams Syndrome Transcription Factor (WSTF)
• Molecular weight: 170 kDa
• Tissue cell line specificity: Sheep
• Target background: The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its Fn motifs include a PHD zinc finger motif followed by a bromodomain. Both motifs are found in many transcription factors, suggesting that WSTF may function as a transcription factor. WSTF forms a chromatinremodelling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The drosophila Ac...

Applications

• Application: IF ; IP ; WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: Whole serum
• Storage conditions: -80° C
• Shipping conditions: Dry ice

References

• Sarshad et al. 2013. PLoS Genet. 9(3):e1003397. PMID: 23555303.
• Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression.
• Bozhenok et al. 2002. EMBO J. 21(9):2231-41. PMID: 11980720.
• WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.