Anti-SPAG1 [10G1/2]

Sperm-associated antigen 1 (SPAG1) has been shown to be expressed in high levels in pancreatic adenocarcinoma. SPAG1 is found in high levels in testis and a large proportion of pancreatic ductal adenocarcinomas (PDAC). It has been seen that in PDAC’s SPAG1 expression is predominantly cytoplasmic and confined to malignant cells. The extent and intensity of […]

Contributors

Inventor Institute
Tatjana Crnogorac-Jurcevic Queen Mary University of London
Cat. #: 151749
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Developmental biology
Application: IF ; IP ; WB
Target: SPAG1
Reactivity: Human
Clone: 10G1/2
Host: Mouse
Class: Monoclonal
Product description: Sperm-associated antigen 1 (SPAG1) has been shown to be expressed in high levels in pancreatic adenocarcinoma. SPAG1 is found in high levels in testis and a large proportion of pancreatic ductal adenocarcinomas (PDAC). It has been seen that in PDAC's SPAG1 expression is predominantly cytoplasmic and confined to malignant cells. The extent and intensity of SPAG1 expression has been shown to be associated with stage and tumour nodal status and this has led to the suggestion that SPAG1 is a novel marker of PDAC progression.
Conjugation: Unconjugated
Isotype: IgG
Molecular weight: 104 kDa
Immunogen: Synthetic peptide SPA-3 (sequence designed to avoid TPR motifs – KTAPFNKEKERRKIEIQEVNE)
Myeloma used: Sp2/0-Ag14
Target background: Sperm-associated antigen 1 (SPAG1) has been shown to be expressed in high levels in pancreatic adenocarcinoma. SPAG1 is found in high levels in testis and a large proportion of pancreatic ductal adenocarcinomas (PDAC). It has been seen that in PDAC's SPAG1 expression is predominantly cytoplasmic and confined to malignant cells. The extent and intensity of SPAG1 expression has been shown to be associated with stage and tumour nodal status and this has led to the suggestion that SPAG1 is a novel marker of PDAC progression.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Neesse et al. 2007. Oncogene. 26:1533-45. [PMID: 16983343]

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