Cat. #162376
Anti-primase p58 monoclonal antibody [PRI-5G6]
Cat. #: 162376
Sub-type: Primary antibody
Target: Human primase p58
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Helmholtz Munich Core Facility Monoclonal Antibodies
Primary Citation: Weisshart et al. 2000. J. Biol. Chem. 275: 17328-17337. PMID: 10747950
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-primase p58 monoclonal antibody [PRI-5G6]
- Alternate name: Anti human primase p58 monoclonal antibody (clone PRI-5G6)
- Research fields: Cancer;Cell biology
- Clone: PRI-5G6
- Tool type ecom: Antibody
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Rat
- Disease: Cancer
- Application: WB
- Description: Antibody for the human primase p58, or human p58 protein kinase, of PRIM2. Applicable to numerous tumour types - its role in cancer is intimately linked to its essential function in DNA replication and genome maintenance.
- Immunogen: Recombinant primase p58 subunit
- Isotype: IgG1
Target Details
- Target: Human primase p58
- Target alternate names: PRIM2, PriL
- Target background: Primase p58 (also known as PRIM2 or PriL) is a large regulatory subunit of DNA primase, an enzyme crucial for DNA replication in eukaryotes. DNA primase, in complex with DNA polymerase alpha, synthesizes short RNA primers that are essential for initiating new DNA strands on both the leading and lagging strands during DNA replication.
Applications
- Application: WB
References
- Weisshart et al. 2000. J. Biol. Chem. 275: 17328-17337. PMID: 10747950
