Cat. #153491
Anti-Lamin B receptor [BB3SS4B5]
Cat. #: 153491
Unit size: 100 ug
Target: Lamin B receptor
Class: Monoclonal
Application: IHC ; IF ; WB
Reactivity: Human ; Mouse
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Lamin B receptor [BB3SS4B5]
- Alternate name: DHCR 14B antibody, DHCR14B antibody, Integral nuclear envelope inner membrane protein antibody, Lamin-B receptor antibody, LBR antibody, LBR_HUMAN antibody, LMN 2R antibody, LMN2R antibody, MGC941 antibody, PHA antibody, PRO65 antibody
- Research fields: Cell signaling and signal transduction
- Clone: BB3SS4B5
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: C57BL/6
- Reactivity: Human ; Mouse
- Host: Mouse
- Application: IHC ; IF ; WB
- Description: Lamin B Receptor (LBR) is a polytopic inner nuclear membrane protein. Its nucleoplasmic domain interacts with components of the nuclear lamina as well as with chromatin, via HP1. LBR also exhibits C14 sterol reductase activity. Deficiency of LBR in humans results in Pelget-Hu??t anomaly featuring hypolobulated granulocyte nuclei. Homozygous loss of LBR causes Greenberg skeletal dysplasia a fetal lethal disorder associated with defective cholesterol metabolism.
- Immunogen: GST fused to N-terminal fragment of human LBR (amino acids residues 1-211)
- Isotype: IgG1 kappa
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Hela, C2C12, NIE-115
Target Details
- Target: Lamin B receptor
- Target background: Lamin B Receptor (LBR) is a polytopic inner nuclear membrane protein. Its nucleoplasmic domain interacts with components of the nuclear lamina as well as with chromatin, via HP1. LBR also exhibits C14 sterol reductase activity. Deficiency of LBR in humans results in Pelget-Hu??t anomaly featuring hypolobulated granulocyte nuclei. Homozygous loss of LBR causes Greenberg skeletal dysplasia a fetal lethal disorder associated with defective cholesterol metabolism.
Applications
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
