Cat. #158056
Anti-Irisin
Cat. #: 158056
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Irisin
Class: Polyclonal
Application: ELISA ; IHC ; WB
Reactivity: Vertebrates
Host: Rabbit
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Abdo Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Irisin
- Research fields: Cell biology;Immunology
- Tool sub type: Primary antibody
- Class: Polyclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 23 kDa
- Reactivity: Vertebrates
- Host: Rabbit
- Application: ELISA ; IHC ; WB
- Description: Irisin belongs to the class of adipomyokines since it acts both in adipose and muscle tissue (adipokine and myokine) and is a thermogenic protein that promotes energy expenditure by white adipose tissue (WAT) browning. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin is a cleavage protein of fibronectin type III domain 5 (FNDC5). FNDC5 converts to irisin after exercise. Irisin dissipates energy as heat and for this reason its discovery has generated a flurry of research aimed at understanding the mechanisms of energy metabolism. Irisin is expected to be a potential therapeutic agent for the treatment of obesity and its related conditions.The antibody is a valuable research tool to study the mechanism of energy metabolism.
- Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved across all vertebrates.
- Recommended controls: ELISA: peptide immunogen, recombinant protein WB: recombinant protein IHC: formalin-fixed, paraffin-embedded fish liver tissues
Target Details
- Target: Irisin
- Molecular weight: 23 kDa
- Tissue cell line specificity: Rabbit
- Target background: Irisin belongs to the class of adipomyokines since it acts both in adipose and muscle tissue (adipokine and myokine) and is a thermogenic protein that promotes energy expenditure by white adipose tissue (WAT) browning. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin is a cleavage protein of fibronectin type III domain 5 (FNDC5). FNDC5 converts to irisin after exercise. Iris...
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Storage buffer: Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal
- Shipping conditions: Shipping at 4° C
