Anti-IgM [BC] mAb

Monoclonal antibody used to monitor vaccine performance in fish.

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited, Scotland
Cat. #: 153308
Unit size: 100 ug
Application: ELISA ; FACS ; IHC ; IP ; WB
Target: Immunoglobulin Heavy Constant Mu (IgM)
Reactivity: Salmon ; Rainbow Trout
Clone: BC
Host: Mouse
Class: Monoclonal
Alternate name: IgM, IgM heavy chain constant region antibody, Immunoglobulin mu antibody, Constant region of heavy chain of IgM antibody, Immunoglobin heavy chain mu constant region antibody
Product description: Monoclonal antibody used to monitor vaccine performance in fish. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. Detection of specific antibodies in the serum of animals is an indicator of previous exposure to pathogens which is very valuable for brood stock health testing. This anti-IgM antibody provides a useful tool to monitor vaccine performance in fish and will assist in the development of future vaccines.
Conjugation: Unconjugated
Isotype: IgG1 kappa
Immunogen: Ammonium sulphate precipitated rainbow trout Ig fraction
Myeloma used: P3X63Ag8.653
Target background: Monoclonal antibody used to monitor vaccine performance in fish. Background and Research Application IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. Detection of specific antibodies in the serum of animals is an indicator of previous exposure to pathogens which is very valuable for brood stock health testing. This anti-IgM antibody provides a useful tool to monitor vaccine performance in fish and will assist in the development of future vaccines.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Ichai et al. 2019. Curr Infect Dis Rep. 21(7):25. PMID: 31165271.

Vasquez et al. 2015. PLoS One. 10(10):e0139718. PMID: 26439739.

Images

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ELISA - Anti-IgM [BC] used to monitor Rainbow Trout Anti-rYRF IgM levels following immunisation with a recombinant protein rYRF.

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