Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Clone 35 can be used for HLA typing, cytotoxic, binding and biochemical assays.
| Inventor | Institute |
|---|---|
| Nancy Hogg | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151046 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | FACS ; IHC ; IP |
| Target: | Human Leukocyte Antigen (HLA) D/DR, DQ (MHC Class II) |
| Reactivity: | Human |
| Clone: | 35 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Clone 35 can be used for HLA typing, cytotoxic, binding and biochemical assays. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG3 |
| Immunogen: | Hairy gene product |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). Clone 35 can be used for HLA typing, cytotoxic, binding and biochemical assays. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Allen et al. 1987. Cancer Res. 47(11):2919-23. PMID: 3105871. Association of colorectal tumor epithelium expressing HLA-D/DR with CD8-positive T-cells and mononuclear phagocytes. |
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