#152694

Anti-DNA Ligase 1 [7A12]

Cat. #152694

Anti-DNA Ligase 1 [7A12]

Cat. #: 152694

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: DNA Ligase 1

Class: Monoclonal

Application: WB ; ELISA ; IHC ; IP ; WB

Reactivity: Bovine ; Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Julian Gannon

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-DNA Ligase 1 [7A12]
  • Research fields: Genetics
  • Clone: 7A12
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 125 kDa
  • Strain: Balb/c
  • Reactivity: Bovine ; Human
  • Host: Mouse
  • Application: WB ; ELISA ; IHC ; IP ; WB
  • Description: DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway.
  • Immunogen: Bovine DNA Ligase I
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: DNA Ligase 1
  • Molecular weight: 125 kDa
  • Target background: DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway.

Applications

  • Application: WB ; ELISA ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Liang et al. 2008. Nucleic Acids Res. 36(10):3297-310. PMID: 18440984.
  • Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.
  • Prigent et al. 1994. Mol Cell Biol. 14(1):310-7. PMID: 8264597.
  • Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I.