E23.1 is extremely sensitive for immunoblotting Cyclin A.
| Inventor | Institute |
|---|---|
| Julian Gannon | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151088 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Genetics |
| Application: | FACS ; IHC ; IF ; IP ; WB |
| Target: | Cyclin A |
| Reactivity: | Mammalian |
| Clone: | E23.1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CCNA1; Cyclin A1; Testicular Tissue Protein Li 34; CT146 |
|---|---|
| Product description: | Anti-CyclinA E23.1 is extremely sensitive for immunoblotting Cyclin A. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | Bovine Cyclin A fusion protein. |
| Immunogen Uniprot ID: | P17927 |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Hagen et al. 2013. Cell Div. 8(1):10. PMID: 23886499. Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis. Li et al. 2012. Proc Natl Acad Sci U S A. 109(31):12550-5. PMID: 22802651. Gap 1 phase length and mouse embryonic stem cell self-renewal. Hogg et al. 2011. Free Radic Biol Med. 50(9):1065-74. PMID: 21256959. Effect of nitric oxide on neointimal hyperplasia based on sex and hormone status. Geley et al. 2001. J Cell Biol. 153(1):137-48. PMID: 11285280. Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. Adamczewski et al. 1993. J Virol. 67(11):6551-7. PMID: 8411358. Simian virus 40 large T antigen associates with cyclin A and p33cdk2. |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151021 | Anti-CyclinB1 [V152] |
Key Info
Anti-CyclinB1 [V152]
|
View Tool | |||||||||||||||||||
| 151022 | Anti-IL12 [1-1A4] |
Key Info
Anti-IL12 [1-1A4]
|
View Tool | |||||||||||||||||||
| 151023 | Anti-IL12 [1-1D5] |
Key Info
Anti-IL12 [1-1D5]
|
View Tool | |||||||||||||||||||
| 151034 | Anti-HSVUL42 [13D11] |
Key Info
Anti-HSVUL42 [13D11]
|
View Tool | |||||||||||||||||||
| 151039 | Anti-Integrin aVb3 [23C6] |
Key Info
Anti-Integrin aVb3 [23C6]
|
View Tool | |||||||||||||||||||
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.