Cat. #151068
Anti-cMyc [9E11]
Cat. #: 151068
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: cMyc
Class: Monoclonal
Application: ChIP ; FACS ; IHC ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Gerard Evan
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-cMyc [9E11]
- Cancer: Gynaecologic cancer;Digestive / Gastrointestinal cancer;Breast cancer;Lung cancer
- Cancers detailed: Cervix;Colorectal;Breast cancer;Lung;Stomach;Broadly Applicable
- Research fields: Cancer;Cell biology;Genetics;Stem cell biology
- Clone: Array
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ChIP ; FACS ; IHC ; IP ; WB
- Description: The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients.
- Immunogen: Residues 408-420. AEEQKLISEEDL.
- Immunogen uniprot id: P01106
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: cMyc
- Target background: The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients.
Applications
- Application: ChIP ; FACS ; IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-cMyc [9E10]
References
- Mittal et al. 2013. PLoS One. 8(8):e70352. PMID: 23936412.
- Role of CTLA4 in the proliferation and survival of chronic lymphocytic leukemia.
- Mirzaei et al. 2013. Proc Natl Acad Sci U S A. 110(9):3645-50. PMID: 23388641.
- Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins.
- Keyhanfar et al. 2007. Biochem J. 401(1):269-77. PMID: 16981855.
- Precise mapping of an IGF-I-binding site on the IGF-1R.
- Halm...
