Anti-Cisplatin modified DNA [CP9/19]

Cat. #151464

Anti-Cisplatin modified DNA [CP9/19]

Cat. #: 151464

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Cisplatin modified native DNA

Class: Monoclonal

Application: ELISA ; FACS ; IHC ; IP ; DB

Host: Rat


This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.


Inventor: Michael Tilby

Institute: The Institute of Cancer Research; Newcastle University

Tool Details
Target Details
Related Tools

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Cisplatin modified DNA [CP9/19]
  • Cancers detailed: Broadly Applicable;Chemotherapy
  • Research fields: Cancer;Genetics
  • Clone: CP9/19
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Host: Rat
  • Application: ELISA ; FACS ; IHC ; IP ; DB
  • Description: Antibody CP9/19 recognises only the intra-strand cross-links formed by cisplatin between adjacent purines.
  • Immunogen: Cisplatin modified native DNA
  • Isotype: IgG2a
  • Myeloma used: Y3.AG.1.2.3
  • Recommended controls: RNA/DNA

Target Details

  • Target: Cisplatin modified native DNA
  • Tissue cell line specificity: RNA/DNA
  • Target background: This antibody enables the quantification of cisplatin-induced adducts on DNA. This antibody has also been recently used for isolation of DNA fragments carrying adducts to enhance the sensitivity of subsequent PCR-based analyses and is central to ongoing studies of variation in the nature of cisplatin adducts formed in different cell lines.


  • Application: ELISA ; FACS ; IHC ; IP ; DB


  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-Cisplatin modified DNA, Recombinant [CP9/19]


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  • 3D-DIP-Chip: a microarray-based method to measure genomic DNA damage.
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  • Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.
  • Kothandapani et al. 2011. J Biol Chem. 286(16):14564-74. PMID: 21357694.
  • Novel role of base excision repair in mediating cisplatin cytotoxicity.
  • Meczes et al. 2005. Biochem Pharmacol. 70(12):1...