Cat. #151452
Anti-CD45 [BU64]
Cat. #: 151452
Unit size: 100 ug
Availability: 3-4 weeks
Target: Protein tyrosine phosphatase, receptor type, C (PTPRC, CD45)
Class: Monoclonal
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Margaret Goodall ; D.L. Hardie ; Roy Jefferis ; Ian MacLennen
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD45 [BU64]
- Alternate name: Anti-PTPRC
- Research fields: Cell biology;Cell signaling and signal transduction;Immunology;Neurobiology;Stem cell biology;Tissue-specific biology
- Clone: BU64
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Host: Mouse
- Description: PTPRC, also know as CD45, is a transmembrane tyrosine phosphatase that is present on all leukocytes. It regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn).
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Protein tyrosine phosphatase, receptor type, C (PTPRC, CD45)
- Target background: PTPRC is a transmembrane tyrosine phosphatase that is present on all leukocytes. PTPRC regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn).
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: RPMI 1640 + 10% FCS
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
