Cat. #152812
Anti-BORIS [20B11] mAb
Cat. #: 152812
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: BORIS
Class: Monoclonal
Application: ChIP ; ELISA ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Elena Klenova
Institute: University of Essex
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-BORIS [20B11] mAb
- Alternate name: Brother of the regulator of imprinted sites, Cancer/testis antigen 27, CCCTC binding factor (zinc finger protein) like, CCCTC-binding factor, CT27, CTCF paralog, CTCF T, CTCF-like protein, Ctcfl, CTCFL_HUMAN, dJ579F2.2, HMG 1L1, HMGB1L1, MGC163358, MGC16915, MGC16916
- Cancer: Genitourinary cancer
- Cancers detailed: Testis
- Research fields: Cancer;Genetics
- Clone: 20B11
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 83 kDa
- Reactivity: Human
- Host: Mouse
- Application: ChIP ; ELISA ; IHC ; IF ; IP ; WB
- Description: Reagent for research, diagnostic tool. BORIS protein has been identified as Cancer-Testis Antigen (CTA) with testis-specific paralogue of the CCCTC-binding factor. Recent studies have demonstrated that d BORIS is directly responsible for the transcriptional activation of TSP50 (testes-specific protease 50).
- Immunogen: Synthetic peptide within the BORIS C-terminal domain (aa 614-648) (CG)GEMFPVACRETTARVKEE (NB - the first two aa do not belong to BORIS)
- Isotype: IgG3 kappa
- Recommended controls: MCF7 cell lysates
Target Details
- Target: BORIS
- Molecular weight: 83 kDa
- Tissue cell line specificity: MCF7 cell lysates
- Target background: BORIS protein has been identified as Cancer-Testis Antigen (CTA) with testis-specific paralogue of the CCCTC-binding factor. Recent studies have demonstrated that d BORIS is directly responsible for the transcriptional activation of TSP50 (testes-specific protease 50).
Applications
- Application: ChIP ; ELISA ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-BORIS [4A7]
References
- Debruyne et al. 2019. Nature. 572(7771):676-680. PMID: 31391581.
