Anti-Bam32 [4H9]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-Bam32 [4H9]
• Research fields: Cell signaling and signal transduction;Immunology
• Clone: 4H9
• Tool sub type: Primary antibody
• Class: Monoclonal
• Purpose: Marker
• Conjugation: Unconjugated
• Reactivity: Human
• Host: Mouse
• Application: WB
• Description: B lymphocyte-associated adaptor protein (Bam32) is 32 kDa and is expressed in high levels in the germinal center (GC) of B cells. It consists of a src homology 2 (SH2) domain at the NH2 terminal which binds phospholipase C (PLC) gamma 2 and a pleckstrin homology (PH) domain at the COOH-terminal. Bam32 acts as an adaptor that integrates protein tyrosine kinase (PTK) and phosphatidylinositol 3-kinase (PI3K) necessary for signaling in B cells. Bam32 is recruited to the plasma membrane upon B cel...
• Immunogen: GST-Bam32 fusion protein
• Isotype: IgG1
• Myeloma used: Sp2/0-Ag14
• Recommended controls: A20 cell lysate

Target Details

• Target: B lymphocyte-associated adaptor protein
• Tissue cell line specificity: Mouse
• Target background: B lymphocyte-associated adaptor protein (Bam32) is 32 kDa and is expressed in high levels in the germinal center (GC) of B cells. It consists of a src homology 2 (SH2) domain at the NH2 terminal which binds phospholipase C (PLC) gamma 2 and a pleckstrin homology (PH) domain at the COOH-terminal. Bam32 acts as an adaptor that integrates protein tyrosine kinase (PTK) and phosphatidylinositol 3-kinase (PI3K) necessary for signaling in B cells. Bam32 is recruited to the plasma membrane upon B cel...

Applications

• Application: WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C