Cat. #157995
anti- HIV-1 protease iBody small molecule (tool compound)
Cat. #: 157995
Availability: Please enquire for quantities and pricing
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jan Tykvart ; Frantisek Sedlak ; Pavel Majer ; Petr Cigler ; Vaclav Navratil ; Vladimir Subr ; Karel Ulbich ; Jiri Strohalm ; Jan Konvalinka ; Jirí Schimer ; Tomas Knedlik ; Sacha Pavel
Institute: Institute of Organic Chemistry and Biochemistry ; Institute of Macromolecular Chemistry ; Charles University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: anti- HIV-1 protease iBody small molecule (tool compound)
- Alternate name: HIV-1 PR; HIV-1 protease; HIV-2 protease; HIV1 PR; HIV2 PR; HIV1 protease
- Research fields: Cell biology;Cell signaling and signal transduction;Immunology
- Description: HIV-1 protease is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. - iBodiesÂŽ are capable of replacing antibodies in biomedical applications such as ELISA, flow cytometry, confocal microscopy, immunocytochemistry, Western Blot and immunoprecipitation. - These iBodiesÂŽ consist of an N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer decorated with low-...
- Additional notes: iBodies(R) is a registered trade mark of IOCB Tech s.r.o.
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References
- Ĺ imon et al. 2018. ACS Chem Biol. 13(12):3333-3342. PMID: 30489064.
- DvoĹĂĄkovĂĄ et al. 2017. J Med Chem. 60(20):8385-8393. PMID: 28953383.
- Ĺ ĂĄcha et al. 2016. Angew Chem Int Ed Engl. 55(7):2356-60. PMID: 26749427.
