![Western blotting was performed on matrix metalloproteinases (MMPs) 1; 2; 3 and 9 in both proenzyme and activated forms using anti-activated MMP1 [5C10] antibody. An approximately 40kDa protein was detected for activated MMP1.](https://cancertools.org/wp-content/uploads/3b7afacf-d070-44bf-a425-cd28041f34fb.png)
Cat. #152766
Anti-activated MMP1 [5C10]
Cat. #: 152766
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: activated human matrix metalloproteinase 1 (MMP1)
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-activated MMP1 [5C10]
- Alternate name: actMMP-1, actMMP1, activated-MMP1, activated MMP1, activated-MMP-1, activated MMP-1, Fibroblast collagenase
- Research fields: Cancer;Cell signaling and signal transduction;Tissue-specific biology
- Clone: 5C10
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 40 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: WB
- Description: Matrix metalloproteinases (MMPs) are synthesized as inactiveÄÂĂÂ zymogensÄÂĂÂ with a pro-peptide domain that must be removed before theÄÂĂÂ enzymeÄÂĂÂ is active.ÄÂĂÂ MMP1 breaks down the interstitialÄÂĂÂ collagens, types I, II, and III hence itÄÂĂÂ is an important feature of development, morphogenesis, tissue repair andÄÂĂÂ remodeling. The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9.
- Immunogen: Ovalbumin-conjugated synthetic peptide; FVLTEGNPRC
- Isotype: IgG1 kappa
- Myeloma used: P3X63Ag8.653
- Recommended controls: Activated recombinant MMP-1
Target Details
- Target: activated human matrix metalloproteinase 1 (MMP1)
- Molecular weight: 40 kDa
- Tissue cell line specificity: Activated recombinant MMP-1
- Target background: Matrix metalloproteinases (MMPs) are synthesized as inactivezymogenswith a pro-peptide domain that must be removed before theenzymeis active.MMP1 breaks down the interstitialcollagens, types I, II, and III hence itis an important feature of development, morphogenesis, tissue repair andremodeling. The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9.
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
