Anti-SPATA25 [Z37P3H11*B2]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-SPATA25 [Z37P3H11*B2]
• Alternate name: Testis-specific gene 23 protein
• Research fields: Developmental biology
• Clone: Z37P3H11*B2
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 23
• Strain: Balb/c
• Reactivity: Human
• Host: Mouse
• Application: ELISA ; IHC ; WB
• Description: SPATA25 (spermatogenesis-associated protein 25), also known as TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that is thought to play a role in spermatogenesis. Predominantly expressed in testis, SPATA25 is found at 60-fold higher levels in adult testis than fetal testis. The gene encoding SPATA25 maps to human chromosome 20q13.12 and mouse chromosome 2 H3. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception.
• Immunogen: Peptide Sequence – LVRSKRGQP
• Isotype: IgG
• Myeloma used: P3X63Ag8.653
• Recommended controls: Jurkat cell lysate

Target Details

• Target: Spermatogenesis Associated 25 (SPATA25)
• Molecular weight: 23
• Target background: SPATA25 (spermatogenesis-associated protein 25), also known as TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that is thought to play a role in spermatogenesis. Predominantly expressed in testis, SPATA25 is found at 60-fold higher levels in adult testis than fetal testis. The gene encoding SPATA25 maps to human chromosome 20q13.12 and mouse chromosome 2 H3. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception.

Applications

• Application: ELISA ; IHC ; WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Shipping at 4° C