#154063

AAV.hSynapsin.iGluSnFR vector

Cat. #154063

AAV.hSynapsin.iGluSnFR vector

Cat. #: 154063

Sub-type: pAAV

Availability: Please enquire for quantities and pricing

Target: SF-iGluSnFR.A184S

Bacterial Resistance: Ampicillin

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Howard Hughes Medical Institute

Tool Details
Target Details
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Tool name: AAV.hSynapsin.iGluSnFR vector
  • Research fields: Cell biology;Neurobiology
  • Tool sub type: pAAV
  • Backbone size without insert: 4373
  • Bacterial resistance: Ampicillin
  • Description: This plasmid has an intensity-based glutamate-sensing fluorescent reporter (“iGluSnFRâ€�) to be used to visualize the fluorescence change during glutamate release by neurons and astrocytes during in vivo imaging. This glutamate sensor is constructed from E. coli Gltl and cpGFP. This adeno-associated virus under the human synapsin-1 promoter drives expression of iGluSnFR in neurons.
  • Additional notes: This plasmid has an intensity-based glutamate-sensing fluorescent reporter (“iGluSnFRâ€�) to be used to visualize the fluorescence change during glutamate release by neurons and astrocytes during in vivo imaging. This glutamate sensor is constructed from E. coli Gltl and cpGFP. This adeno-associated virus under the human synapsin-1 promoter drives expression of iGluSnFR in neurons.

Target Details

  • Target: SF-iGluSnFR.A184S

References

  • Marvin et al. 2013. Nat Methods. 10(2):162-70. PMID: 23314171.
  • An optimized fluorescent probe for visualizing glutamate neurotransmission.