Cat. #154064
AAV.GFAP.iGluSnFR vector
Cat. #: 154064
Sub-type: pAAV
Availability: Please enquire for quantities and pricing
Bacterial Resistance: Ampicillin
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Howard Hughes Medical Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: AAV.GFAP.iGluSnFR vector
- Research fields: Cell biology;Neurobiology
- Tool sub type: pAAV
- Bacterial resistance: Ampicillin
- Description: This plasmid has an intensity-based glutamate-sensing fluorescent reporter (“iGluSnFR�) to be used to visualize the fluorescence change during glutamate release by neurons and astrocytes during in vivo imaging. This glutamate sensor is constructed from E. coli Gltl and cpGFP. This adeno-associated virus under the glial fibrillary acidic protein promoter drives expression in astrocytes.
- Additional notes: This plasmid has an intensity-based glutamate-sensing fluorescent reporter (“iGluSnFR�) to be used to visualize the fluorescence change during glutamate release by neurons and astrocytes during in vivo imaging. This glutamate sensor is constructed from E. coli Gltl and cpGFP. This adeno-associated virus under the glial fibrillary acidic protein promoter drives expression in astrocytes.
References
- Marvin et al. 2013. Nat Methods. 10(2):162-70. PMID: 23314171.
- An optimized fluorescent probe for visualizing glutamate neurotransmission.
